"Myeloperoxidase-Halide-Hydrogen Peroxide Antibacterial System"
Seymour J. Klebanoff
Journal of Bacteriology
June, 1968
Volume
95, Number 6
Pages2131-2138
PMID: 4970226 [PubMed - indexed for MEDLINE]
A quote from the following paper...
"H2O2 alone has antibacterial properties; however, the antibacterial effect of H2O2
is increased many orders of magnitude by the addition of myeloperoxidase and iodide, bromide, or chloride ions. The
concentration of H2O2 routinely used for complete bacterial killing in the study reported here was 0.00005 M, and a lesser
antibacterial effect was observed with smaller concentrations. Thus, the H2O2 formed in leukocytes following phagocytosis
appears to be present in concentrations adequate to function as a component of the myeloperoxidase-mediated antibacterial
system"
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