"Role of Oxygen-Dependent Mechanisms in Antibody-Induced Lysis of Tumor Cells
by Activated Macrophages"
Carl Nathan and Zanvil Cohn
Journal of Experimental Medicine July,
1980
Volume 152
Pages 198-208PMID: 6995553 [PubMed - indexed for MEDLINE]
A quote from the following paper...
"Previous work by other investigators makes it likely that activated macrophages produce
reactive metabolites of oxygen during interaction with antibody-coated tumor cells. The... lysis of... lymphoma cells...was
inhibited 62% by depletion of oxygen. The extracellular lysis of antibody-coated lymphoma cells by... macrophages appears
to have a predominantly oxidative basis."
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